Hi Robert,

 

I was able to load the dataset in the development version of R (which is higher than 4.0):

 

********

> library(Seurat)

> d <- readRDS("blish_covid.seu.rds")

> d

An object of class Seurat

52722 features across 44721 samples within 2 assays

Active assay: SCT (26361 features, 3000 variable features)

1 other assay present: RNA

2 dimensional reductions calculated: pca, umap

> sessionInfo()

R Under development (unstable) (2020-09-24 r79253)

Platform: x86_64-apple-darwin17.0 (64-bit)

Running under: macOS High Sierra 10.13.6

 

Matrix products: default

BLAS:   /Library/Frameworks/R.framework/Versions/4.1/Resources/lib/libRblas.dylib

LAPACK: /Library/Frameworks/R.framework/Versions/4.1/Resources/lib/libRlapack.dylib

 

locale:

[1] en_GB.UTF-8/en_GB.UTF-8/en_GB.UTF-8/C/en_GB.UTF-8/en_GB.UTF-8

 

attached base packages:

[1] stats     graphics  grDevices utils     datasets  methods   base

 

other attached packages:

[1] Seurat_3.2.2

 

loaded via a namespace (and not attached):

[1] nlme_3.1-149          matrixStats_0.56.0    RcppAnnoy_0.0.16

[4] RColorBrewer_1.1-2    httr_1.4.2            sctransform_0.3.1

[7] tools_4.1.0           R6_2.4.1              irlba_2.3.3

[10] rpart_4.1-15          KernSmooth_2.23-17    uwot_0.1.8

[13] lazyeval_0.2.2        mgcv_1.8-33           colorspace_1.4-1

[16] tidyselect_1.1.0      gridExtra_2.3         compiler_4.1.0

[19] plotly_4.9.2.1        scales_1.1.1          lmtest_0.9-38

[22] spatstat.data_1.4-3   ggridges_0.5.2        pbapply_1.4-3

[25] spatstat_1.64-1       goftest_1.2-2         stringr_1.4.0

[28] digest_0.6.25         spatstat.utils_1.17-0 pkgconfig_2.0.3

[31] htmltools_0.5.0       fastmap_1.0.1         htmlwidgets_1.5.2

[34] rlang_0.4.7           shiny_1.5.0           generics_0.0.2

[37] zoo_1.8-8             jsonlite_1.7.1        ica_1.0-2

[40] dplyr_1.0.2           magrittr_1.5          patchwork_1.0.1

[43] Matrix_1.2-18         Rcpp_1.0.5            munsell_0.5.0

[46] abind_1.4-5           reticulate_1.18       lifecycle_0.2.0

[49] stringi_1.5.3         MASS_7.3-53           Rtsne_0.15

[52] plyr_1.8.6            grid_4.1.0            parallel_4.1.0

[55] listenv_0.8.0         promises_1.1.1        ggrepel_0.8.2

[58] crayon_1.3.4          miniUI_0.1.1.1        deldir_0.1-29

[61] lattice_0.20-41       cowplot_1.1.0         splines_4.1.0

[64] tensor_1.5            pillar_1.4.6          tcltk_4.1.0

[67] igraph_1.2.6          future.apply_1.6.0    reshape2_1.4.4

[70] codetools_0.2-16      leiden_0.3.3          glue_1.4.2

[73] data.table_1.13.2     png_0.1-7             vctrs_0.3.4

[76] httpuv_1.5.4          gtable_0.3.0          RANN_2.6.1

[79] purrr_0.3.4           polyclip_1.10-0       tidyr_1.1.2

[82] future_1.19.1         ggplot2_3.3.2         rsvd_1.0.3

[85] mime_0.9              xtable_1.8-4          later_1.1.0.1

[88] survival_3.2-3        viridisLite_0.3.0     tibble_3.0.3

[91] cluster_2.1.0         globals_0.13.1        fitdistrplus_1.1-1

[94] ellipsis_0.3.1        ROCR_1.0-11

 

********

 

Could you check again on your side?

 

We will also add md5sums to the website later today.

 

Hope this helps,

Cheers,

Vlad

 

--

Vladimir Kiselev

 

CellGen Informatics Team Leader

Wellcome Sanger Institute

Wellcome Genome Campus

Hinxton, Cambridge, CB10 1SA

Phone: +44 (0) 1223 496850

Message: Mattermost or Slack

Web: https://wikiselev.github.io

 

 

From: "Gentleman, Robert C." <Robert_Gentleman@hms.harvard.edu>
Date: Monday, 26 October 2020 at 17:05
To: "cv19caingest@sanger.ac.uk" <cv19caingest@sanger.ac.uk>
Subject: [Cv19caingest] want to report a problem [EXT]

 

Hi

  Sorry to send to this address but I could not find out where to report problems.  I wanted to download and use this file

https://urldefense.proofpoint.com/v2/url?u=https-3A__hosted-2Dmatrices-2Dprod.s3-2Dus-2Dwest-2D2.amazonaws.com_Single-5Fcell-5Fatlas-5Fof-5Fperipheral-5Fimmune-5Fresponse-5Fto-5FSARS-5FCoV-5F2-5Finfection-2D25_blish-5Fcovid.seu.rds&d=DwIFAw&c=D7ByGjS34AllFgecYw0iC6Zq7qlm8uclZFI0SqQnqBo&r=YCVDjNHxAgv8-gpjr0Xb48Y9Vk9U8oXzH6wskU6pf14&m=jHyycfiwLK3bOVXgQlFZhA6J8LKGcQd-cymrZIfTun0&s=kXGQNkvh8M8iNbCfkfHKNwoHQVp5XcLBwOmh5eioMEk&e=

 

   Which is supposed to be an R data set, unfortunately it is not and is corrupted or otherwise not valid (could be they used a very old version of R, but no information is provided on your website).

 

It would be helpful to provide md5 checksums or other tools to help

validate downloads etc.

 

  Robert