Imaging mass cytometry data as part of the COVID-19 cell atlas? [EXT]
Hello, We've recently generated spatially-resolved single-cell data of post-mortem lung tissue of COVID-19 patients and other lung infections (https://urldefense.proofpoint.com/v2/url?u=https-3A__www.medrxiv.org_content_10.1101_2020.10.26.20219584v1&d=DwIDaQ&c=D7ByGjS34AllFgecYw0iC6Zq7qlm8uclZFI0SqQnqBo&r=YCVDjNHxAgv8-gpjr0Xb48Y9Vk9U8oXzH6wskU6pf14&m=Cdg2YY0Q4Zd5j30e_fYJlgBCVLfqFCQwx_wanKJzz1s&s=RxbqAWtsvUopbe2942RB2lIYmN834ZyAWmd3ZRmOfeI&e= ). Would there be interest in adding this dataset to the COVID-19 portal of the HCA? We already provide a h5ad file with the single-cell data (https://urldefense.proofpoint.com/v2/url?u=https-3A__zenodo.org_record_4139443_files_results_covid-2Dimc.h5ad&d=DwIDaQ&c=D7ByGjS34AllFgecYw0iC6Zq7qlm8uclZFI0SqQnqBo&r=YCVDjNHxAgv8-gpjr0Xb48Y9Vk9U8oXzH6wskU6pf14&m=Cdg2YY0Q4Zd5j30e_fYJlgBCVLfqFCQwx_wanKJzz1s&s=fPD9wTkARNTbfU9L9zT3gVZjoAkLj7DqhwN3amEV1cw&e= ), but perhaps this could help researchers having a one-stop place for COVID-19 single cell data? Of importance, our features do not represent gene expression but protein abundance for 36 selected proteins, so this is in contrast to most other datasets which I believe are scRNA-seq. Best wishes, Andre -- *André Rendeiro, Ph.D. *Postdoctoral Associate, Elemento Lab Englander Institute for Precision Medicine Institute for Computational Biomedicine *Weill Cornell Medicine *1305 York Ave., Y13.13 New York, NY (USA) 10021 afr4001@med.cornell.edu <mailto:afr4001@med.cornell.edu>
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Andre Rendeiro